Reconstitution of CPSF active in polyadenylation: recognition of the polyadenylation signal by WDR33
نویسندگان
چکیده
منابع مشابه
Reconstitution of CPSF active in polyadenylation: recognition of the polyadenylation signal by WDR33.
Cleavage and polyadenylation specificity factor (CPSF) is the central component of the 3' processing machinery for polyadenylated mRNAs in metazoans: CPSF recognizes the polyadenylation signal AAUAAA, providing sequence specificity in both pre-mRNA cleavage and polyadenylation, and catalyzes pre-mRNA cleavage. Here we show that of the seven polypeptides that have been proposed to constitute CPS...
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ژورنال
عنوان ژورنال: Genes & Development
سال: 2014
ISSN: 0890-9369,1549-5477
DOI: 10.1101/gad.250985.114